Biopharmaceutical Process Technologies For Reliable Manufacturing Operations

Parker Hannifin deployed automated filtration and single-use processing systems to support pharmaceutical and biopharmaceutical manufacturing operations. The engineered solutions are designed to address supply chain uncertainties and contamination risks in critical fluid processing environments.

Addressing the Industrial Challenge
Pharmaceutical producers must adapt to stringent regulatory frameworks, including EU GMP Annex 1, while executing mandated Pre-Use Post Sterilization Integrity Testing workflows. Managing fluid contamination risks without introducing unnecessary process complexity requires specialized, highly controlled equipment. Facilities also require robust mechanical infrastructure to mitigate global supply chain fluctuations through dual sourcing strategies and reduced stock-keeping unit complexity.

Technical Architecture and System Capabilities
The technical infrastructure relies on PureTain Single-Use Assemblies integrated with the SciLog NFF+ Automated System. The SciLog platform utilizes precision pumps and sensors to execute automated Pre-Use Post Sterilization Integrity Testing, verifying filtration parameters during critical processing stages. The system architecture incorporates PROPOR sterilizing grade filters, deploying high-area models to maximize volumetric throughput. To support emerging chemical and material regulations, the technical portfolio includes PFAS-free filter options, allowing operators to maintain validated compliance parameters and product quality without performance degradation.

Deployment and Operational Impact
These processing technologies are implemented across bioprocessing environments, drug delivery systems, active pharmaceutical ingredient production, and contract manufacturing facilities. By streamlining fluid flow paths, the integrated systems directly reduce potential contamination sites within the manufacturing infrastructure. Jean-Philippe Minne, platform sales leader Biopharma at Parker Hannifin, stated: "Pharmaceutical manufacturers are under increasing pressure to strengthen process reliability, reduce contamination risk, and maintain compliance while keeping operations efficient." The technical integration of these single-use and automated filtration systems provides measurable operational stability for production teams. The equipment and technical frameworks will be demonstrated at CPHI 2026, taking place from October 6 to 8, 2026, in Milan.

Edited by Maria Brueva, Induportals editor – adapted by AI.

www.parker.com